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SUNGSAM GONG

(공성삼,  孔聖參)

Crystallography and Biocomputing Unit
Department of Biochemistry
University of Cambridge
Tennis Court Road, Cambridge, UK
Tel : 01223  766  033

Personal Details

Name:
     English : SUNGSAM GONG
     Korean Name: 공성삼
Date of Birth: 15th, March, 1976
Marital Status: Single
Nationality: Korean
Present affiliation: Department of BiochemistryUniversity of Cambridge
Position: PhD student
Address:
     Home Address: 193 Cherry Hinton Road, Cambridge, UK
     Work  Address: Sanger Building (Old Addenbrookes site), Department of Biochemistry, Tennis Court Road, Cambridge, UK 
Contact Info : sung@bio.cc, ssg29@cam.ac.uk (Office: +44-1223-766033) 

Educational Background

2006. 10 ~ now:    PhD candidate, Univeristy of Cambridge, Dept. of Biochemistry
2003. 9 ~ 2005. 8:   MSc, KAIST (Korea Advanced Institute of Science and Technology), Department of BioSystems
2002. 3 ~ 2003. 8:   Bsc, Korea University, Department of Computer Science
1999. 3 ~ 2002.2:    Bsc. Korea University, Department of Biology

Employment

2005. 9 ~ 2006. 9 : Researcher at KOBIC (Korean Bioinformation Center), KRIBB (Korea Research Institute of Bioscience and Biotechnology)

Research Interests

(in no particular order)
  • Prediction and modulation of PPI (protein protein interaction) and their interacting interfaces
  • Evolutionary relationship between protein sequence, structure and function
  • Effects of amino acid mutation on protein structure and fuction
  • Association between genotypes and phenotypes, and application in the molecular dianosis
  • Structural and functional restraints of protein evolution

Publications

PubMed Search
  1. Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins
    Gong S, Blundell TL (2010)
    PLoS ONE 5(2): e9186. doi:10.1371/journal.pone.0009186
  2. MitoInteractome: mitochondrial protein interactome database, and its application in 'aging network' analysis
    Reja R, Venkatakrishnan AJ, Lee J, Kim BC, Ryu JW, Gong S, Bhak J, Park D.
    BMC Genomics. 2009 Dec 3;10 Suppl 3:S20.
  3. Structural and functional constraints in the evolution of protein families.
    Worth CL, Gong S, Blundell TL.
    Nat Rev Mol Cell Biol. 2009 Oct;10(10):709-20. Epub 2009 Sep 16.
  4. Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics.
    Lee S, Brown A, Pitt WR, Perez Higueruelo A, Gong S, Bickerton GR, Schreyer A, Tanramluk D, Baylay A, Blundell TL.
    Mol Biosyst. 2009 Aug 6
  5. Structural and functional restraints in the evolution of protein families and superfamilies
    Gong S, Worth CL, Bickerton GR, Lee S, Tanramluk D, Blundell TL.
    Biochem Soc Trans. 2009 Aug;37(Pt 4):727-33
  6. Discarding functional residues from the substitution table improves predictions of active sites within three-dimensional structures
    Gong S., Blundell TL.
    PLoS Comput Biol. 2008 Oct 3;4(10):e1000179.
  7. A STRUCTURAL BIOINFORMATICS APPROACH TO THE ANALYSIS OF NONSYNONYMOUS SINGLE NUCLEOTIDE POLYMORPHISMS (nsSNPs) AND THEIR RELATION TO DISEASE.
    Worth CL, Bickerton GR, Schreyer A, Forman JR, Cheng TM, Lee S, Gong S, Burke DF, Blundell TL.
    J Bioinform Comput Biol. 2007 Dec;5(6):1297-318.
  8. Biological Object Downloader (BOD) Service for Easy Download and Management of Biological Databases.
    Daeui Park, Jungwoo Lee, Giseok Yoon, Sungsam Gong and Jong Bhak.
    Genomics & Informatics, 2007 5(4) 196-199.
  9. BioCC: An Openfree Hypertext Bio Community Cluster for Biology
    Sungsam Gong, TaeHyung Kim, Jungsu Oh, Jekeun Kwon, SuAn Cho, Dan Bolser and Jong Bhak.
    Genomics & Informatics, 2006 4(3) 125-128.
  10. SNP@Domain: a web resource of Single Nucleotide Polymorphisms (SNPs) within protein domain and sequences
    Areum Han, Hyo Jin Kang, Yoobok Cho, Sunghoon Lee, and Sungsam Gong
    Nucleic Acids Research, 2006 Web server issue.
  11. Protein Domain Interaction Interface Database: InterPare
    Gong S, Park C, Choi H, Ko J, Jang I, Lee J, Bolser DM, Oh D, Kim DS, Bhak J.
    BMC Bioinformatics. 2005 Aug 25; 6(1):207
  12. PSIbase: a database of Protein Structural Interactome map (PSIMAP)
    Gong S, Yoon G, Jang I, Bolser D, Dafas P, Schroeder M, Choi H, Cho Y, Han K, Lee S, Choi H, Lappe M, Holm L, Kim S, Oh D, Bhak J.
    Bioinformatics. 2005 May 15;21(10):2541-3
  13. The Atom of Evolution
    Jonghwa Bhak, Dan Bolser, Daeui Park, Yoobok Cho, Kiesuk Yoon, Semin Lee, SungSam Gong, Insoo Jang, Changbum park, Maryana Huston and Hwanho Choi
    Genomics and Informatics, December 2004, 2(4):167-173

Patent

  1. System and Method for Analysis of Interfaces Based on Protein Domain and their ligands and Recording Medium Therefor (KOR:2005-0121684)
  2. System and Method for Searching Materials Interfacing with Proteins Based on Interfaceome and Recording Medium Therefor, (KOR:2006-0062631)

Referee

  • Dr. Jong Bhak (aka. Jong Park), j@bio.cc, jongbhak@yahoo.com, Theragen Bio Institute,  AICT building, Suwon, 443-270, South Korea
  • Professor Sir Tom Blundell, tom@cryst.bioc.cam.ac.uk, Department of Biochemistry, Sanger Building, Tennis court road, Cambridge, CB2 1GA, UK
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